Neonatal diabetes mellitus: A model for personalized medicine
نویسندگان
چکیده
منابع مشابه
Neonatal diabetes mellitus: a model for personalized medicine.
Neonatal diabetes mellitus occurs in approximately 1 out of every 100,000 live births. It can be either permanent or transient, and recent studies indicate that is likely to have an underlying genetic cause, particularly when diagnosed before 6 months of age. Permanent neonatal diabetes is most commonly due to activating mutations in either of the genes encoding the two subunits of the ATP-sens...
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The world is facing an epidemic rise in diabetes mellitus (DM) incidence, which is challenging health funders, health systems, clinicians, and patients to understand and respond to a flood of research and knowledge. Evidence-based guidelines provide uniform management recommendations for "average" patients that rarely take into account individual variation in susceptibility to DM, to its compli...
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متن کاملNeonatal diabetes mellitus.
Diabetes mellitus has many forms. Neonatal diabetes mellitus is one of the rarest, with a reported incidence of 1 in 450,000 live births.1 2 The first case was described by Kitselle (1 852) in his own newborn son, who subsequently died.3 In Northern Ireland, one case might be expected approximately every 16 years; the lastdocumented here was born in 1983.4 Several literature reviews have highli...
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ژورنال
عنوان ژورنال: Trends in Endocrinology & Metabolism
سال: 2010
ISSN: 1043-2760
DOI: 10.1016/j.tem.2010.03.004